Cannabindoids Aren't Just CBD and THC

By Evan G

The buzz about CBD and THC probably exceeds that of the plant itself. Interestingly, these cannabinoids are just a fraction of the total composition of cannabinoids in the plant. The silent contemporaries are namely cannabigerol (CBG), tetrahydrocannabivarin (THCV), and cannabinol (CBN).

The recent increase in the number of research papers dedicated to the benefits of hemp is alarming. A complementary discovery of more components of the plant is only fair. Cannabinoids are known for their synergetic mode of operation. Since they all work together, it is important to map out the areas where they superimpose on each other. With THCV and CBG, scientists have mentioned the possibility of the healing effect of the hemp plant. Because the research itself is in a preliminary stage, you must understand that these cannabinoids are promising.

Cannabigerol (CBG)

Unlike THC, CBG does not result in the usual ‘high’. This is similar to the mode of action of CBD as well. An interesting fact is that both CBD and THC start out as cannabigerol. Produced as cannabigerol acid, specific enzymes break down the acidic form into CBD and THC (initially in the acid forms). As the acid burns off through decarboxylation, the formation of CBD and THC occurs. The importance of CBG is to increase the level of anandamides. This endocannabinoid is responsible for the regulation of memory, sleep, and appetite.

Benefits include:

  • Stimulation of healing and bone formation
  • Slowing down the growth of tumor
  • Antimicrobial and antifungal properties
  • Treatment of glaucoma, psoriasis skin, and overactive bladder

Tetrahydrocannabivarin (THCV)

The THVC is a compound that resembles the THC cannabinoid. Nevertheless, it poses a different effect on the body. Being psychoactive drugs, they cause the regular ‘high’ in users. The process of initiation occurs when the THC binds to the CB1 and CB2 of the body. THCV, on the other hand, will not activate the receptors when in low doses even though it binds to them. This is the point where it acts like CBD. But higher doses will produce a counter effect. Furthermore, THCV exhibits swift responses to activation of the feeling of ‘highness’ and the subsequent fading.


  • Stimulation of bone growth – may be able to address osteoporosis and other bone conditions
  • Anti-convulsive properties
  • Improvement of the control of motor functions
  • Counteracting anxiety and effective for treatment of PTSD

Cannabinol (CBN)

Cannabinol is the end product of THC when it undergoes heating or oxygenation process. Without the capacity to bind to CB1 and CB2 receptors, it is not similar to THC. Because it is non-psychoactive, it will not produce a ‘high’. A rare cannabinoid, a sample of cannabis plant may contain 1% of the cannabinoid.


  • The growth of bone tissue
  • Anti-inflammatory property
  • Great sedative
  • Stimulation of appetite, sleep, and anti-convulsive property

The campaign that consumers of CBD should buy ‘full spectrum extract’ is on. By full spectrum, it means that all the terpenes, flavonoids, and cannabinoids in the plant extract are also present in the resulting CBD oil. It is evident that components of a hemp plant work in consonance. For this reason, full spectrum oil gives an ‘entourage effect’ such that the user can maximize the benefit of a single sample.

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